A new study shows that quercetin can potently enhance mitochondrial biogenesis, even protecting against toxic stress, which often interferes with the process. Mitochondria are your energy-producing engines of your cells. Being able to generate new ones, the process of biogenesis, is a really good idea if you wish to be healthy, as well as live a long time.
It is important to understand that mitochondrial biogenesis takes place when the conditions for it to do so exist. It isn’t that any one nutrient will simply force it to happen. This is why taking good care of yourself does make a large difference, as too much stress and too much toxins make it not happen.
In order to create the environment for mitochondrial biogenesis you should begin by following the five rules of the Leptin Diet. By leaving more time between meals you turn on enzymes and genes that contribute to this process.
In particular, the enzyme AMPK (AMP-activated protein kinase), is better activated by following the Leptin Diet. Quercetin has also been shown to activate AMPK, which helps blood sugar metabolism, and sets the stage for better fat burning. Another member of the team that creates an environment for mitochondrial biogenesis is SIRT1, typically referred to as longevity factor. While resveratrol is best known for this, quercetin can also help.
When these metabolic signals are active, then a third gene signal is more likely to turn on and stay on for a period of time. This gene is called PGC-1a, it is the required gene signal for mitochondrial biogenesis. It also orchestrates fat burning. One of the main enemies of this system is too much inflammation, which turns off mitochondrial biogenesis. The new study shows that quercetin turns on the mitochondrial biogenesis process and helps prevent inflammation from turning it off.
Clearly, quercetin should be part of your anti-aging team.